Structure of PDB 7x51 Chain F

Receptor sequence
>7x51F (length=459) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence]
EDLNFRKGDAKTDVFGSDRMLQPSPVERIPDGPTTPEVAYQMVKDETFAQ
TQPRLNLATFVTTYMDDYATKLMNEAININYIDETEYPRIAVMNGKCINI
VANLWNSPEKDTWKTGALAIGSSEACMLGGVAAWLRWRKKRQAQGKPFDK
PNFVISTGFQVVWEKFAQLWQIEMREVPLTLEKTTLDPEEALKMCDENTI
CVVPIQGVTWTGLNDDVEALDKALDAYNAKTGYDIPIHVDAASGGFILPF
LYPDTKWDFRLKWVLSISVSGHKFGLVYPGLGWVCWKGKEYLPEEMSFSV
NYLGANITQVGLNFSRPAAQILGQYYQFIRLGFQGYKEVQYNSLQIAKYI
HGEIAKMAPFVNYSENVVNPLFIWYLKPEYAKSAKWTLYDLQDKLSQHGW
MVPAYTLPSKLEDYVVMRVVVRQGFSRDMADMLLGDIKNAIAELEKLDFP
TPTRMAQEK
3D structure
PDB7x51 Coordinated regulation of Bacteroides thetaiotaomicron glutamate decarboxylase activity by multiple elements under different pH.
ChainF
Resolution2.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 4.1.1.15: glutamate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GUA F N81 D84 F315 S316 N80 D83 F314 S315
BS02 PLP F G122 S123 S124 Q161 D241 A243 S271 H273 K274 G121 S122 S123 Q160 D240 A242 S270 H272 K273
BS03 GUA F T60 F61 V62 Q161 T210 T59 F60 V61 Q160 T209
Gene Ontology
Molecular Function
GO:0004351 glutamate decarboxylase activity
GO:0016830 carbon-carbon lyase activity
GO:0016831 carboxy-lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006536 glutamate metabolic process
GO:0006538 glutamate catabolic process
GO:0019752 carboxylic acid metabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7x51, PDBe:7x51, PDBj:7x51
PDBsum7x51
PubMed36358099
UniProtQ8A4M9

[Back to BioLiP]