Structure of PDB 7vpd Chain F

Receptor sequence

>7vpdF (length=301) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence]

ATADPVKDYLKQIGKVPLLNAEQEVELAKRIEAGLFAEDKLANSDKLAPK
LKRELEIIAEDGRRAKNHLLEANLRLVVSLAKRYTGRGMLFLDLIQEGNL
GLIRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVI
NKLARVQRQMLQDLGREPTPEELAKELDMTPEKVIEVQKYGREPISLHTP
LGEDGDSEFGDLIEDSEAVVPADAVSFTLLQEQLHSVLDTLSEREAGVVS
MRFGLTDGQPKTLDEIGKVYGVTRERIRQIESKTMSKLRHPSRSQVLRDY
L

3D structure

PDB

7vpd Structural basis of Streptomyces transcription activation by zinc uptake regulator.

Chain

Resolution

3.77 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	F	V215 K216 L219 L227 R284 L285 K291 F300 K317 K322 Y324 K325 S327 T328 W332 W333 Q336 R350 P352 H354 T482 E484 R485	V6 K7 L10 L18 R75 L76 K82 F91 K108 K113 Y115 K116 S118 T119 W123 W124 Q127 R141 P143 H145 T273 E275 R276
BS02	dna	F	R292 R296 R364 R367 G411 E412 D413 L472 D473 R483 E484 R487	R83 R87 R155 R158 G202 E203 D204 L263 D264 R274 E275 R278

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0016987	sigma factor activity

	Biological Process
GO:0006352	DNA-templated transcription initiation
GO:0006355	regulation of DNA-templated transcription
GO:0010468	regulation of gene expression
GO:2000142	regulation of DNA-templated transcription initiation

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7vpd, PDBe:7vpd, PDBj:7vpd
PDBsum	7vpd
PubMed	35871291
UniProt	A0A7U9DYK1

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