Structure of PDB 7v5n Chain F

Receptor sequence

>7v5nF (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]

EVQLVESGGGLVQPGGSLRLSCAASGYTFTNYGMNWVRQAPGKGLEWVGW
INTYTGEPTYAADFKRRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCAKYP
HYYGSSHWYFDVWGQGTLVTVSSASTKGPSVFPLAPGTAALGCLVKDYFP
EPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICN
VNHKPSNTKVDKKVEP

3D structure

PDB

7v5n Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection.

Chain

Resolution

1.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	F	T30 N31 Y32 G33 W50 N52 T53 Y54 T55 Y99 H101 Y102 Y103 G104 S105 W108	T30 N31 Y32 G33 W50 N52 T53 Y54 T55 Y99 H101 Y102 Y103 G104 S105 W108

External links

PDB	RCSB:7v5n, PDBe:7v5n, PDBj:7v5n
PDBsum	7v5n
PubMed	35114463

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