Structure of PDB 7uiv Chain F

Receptor sequence
>7uivF (length=567) Species: 562 (Escherichia coli) [Search protein sequence]
ENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVG
KTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKA
LLKQLEQDTNSILFIDEIHTIINLIKPLLSSGKIRVIGSTTYQEFSNIFE
KDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAV
ELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVAR
IARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLG
HEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSR
LIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMD
NGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEI
KKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVT
VALDKEKNELTYGFQSA
3D structure
PDB7uiv AAA+ protease-adaptor structures reveal altered conformations and ring specialization.
ChainF
Resolution3.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP F L188 R191 G217 V218 G219 T221 A222 I357 L19 R22 G48 V49 G50 T52 A53 I175
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0006979 response to oxidative stress
GO:0034605 cellular response to heat
GO:0043335 protein unfolding
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0009368 endopeptidase Clp complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:7uiv, PDBe:7uiv, PDBj:7uiv
PDBsum7uiv
PubMed36329286
UniProtP0ABH9|CLPA_ECOLI ATP-dependent Clp protease ATP-binding subunit ClpA (Gene Name=clpA)

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