Structure of PDB 7txh Chain F

Receptor sequence
>7txhF (length=294) Species: 9606 (Homo sapiens) [Search protein sequence]
NALNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLE
LEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETI
CLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTD
CFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDL
LWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDG
YEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKP
3D structure
PDB7txh Structure of the MRAS-SHOC2-PP1C phosphatase complex.
ChainF
Resolution1.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN F D64 H66 D92 H248 D60 H62 D88 H244
BS02 MN F D92 N124 H173 H248 D88 N120 H169 H244
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:7txh, PDBe:7txh, PDBj:7txh
PDBsum7txh
PubMed35830882
UniProtP62136|PP1A_HUMAN Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (Gene Name=PPP1CA)

[Back to BioLiP]