Structure of PDB 7t4s Chain F

Receptor sequence
>7t4sF (length=363) Species: 9606 (Homo sapiens) [Search protein sequence]
CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEH
CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAK
DGFSARYYLVHQQCNVPLGMESGRIANEQISTPQQSRLHGDSNKEYLQVD
LRFLTMLTAIATQGYKLEVSTNGEDWMVYFQANNTEVVLNKLHAPLLTRF
VRIRPQLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAA
RLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARARAFVRKF
KVSYSLNGKDWEYIQPKLFEGNMHYDTPDIRRFDPIPAQYVRVYPERWSP
AGIGMRLEVLGCD
3D structure
PDB7t4s Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
ChainF
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA F E197 D211 T251 D252 V255 E49 D54 T94 D95 V98
Gene Ontology
Molecular Function
GO:0005021 vascular endothelial growth factor receptor activity
GO:0017154 semaphorin receptor activity
Biological Process
GO:0001525 angiogenesis
GO:0007411 axon guidance
GO:0038084 vascular endothelial growth factor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t4s, PDBe:7t4s, PDBj:7t4s
PDBsum7t4s
PubMed35275719
UniProtO60462|NRP2_HUMAN Neuropilin-2 (Gene Name=NRP2)

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