Structure of PDB 7p3q Chain F

Receptor sequence
>7p3qF (length=147) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence]
MHCPFCRHPDSRVVDSRTTDDGTSIRRRRQCPDCSRRFTTVETCSLMVVK
RSGVTEPFSRTKVINGVRKACQGRPVTEDALAQLGQRVEEAVRATGSAEL
TTHDVGLAILGPLQELDLVAYLRFASVYRAFDSLEDFEAAIAELRET
3D structure
PDB7p3q A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
ChainF
Resolution3.12 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 DTP F K69 Q72 K69 Q72
BS02 ATP F V48 K50 R51 E56 F58 S59 K62 T102 F124 V48 K50 R51 E56 F58 S59 K62 T102 F124
BS03 DTP F K50 K62 G66 K69 R123 F124 V127 Y128 K50 K62 G66 K69 R123 F124 V127 Y128
BS04 ZN F C3 C6 C31 C3 C6 C31
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:7p3q, PDBe:7p3q, PDBj:7p3q
PDBsum7p3q
PubMed35577776
UniProtO69980|NRDR_STRCO Transcriptional repressor NrdR (Gene Name=nrdR)

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