Structure of PDB 7n5q Chain F

Receptor sequence
>7n5qF (length=278) Species: 10090 (Mus musculus) [Search protein sequence]
GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAP
WMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSG
CDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQS
GAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVT
LRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVP
LGKEQNYTCRVYHEGLPEPLTLRWEPPS
3D structure
PDB7n5q Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus.
ChainF
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide F Y7 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 E163 W167 Y171 Y7 E63 K66 Q70 W73 V76 S77 N80 L81 Y84 Q97 Y123 T143 K146 W147 S150 A152 H155 Y156 Y159 E163 W167 Y171
External links
PDB RCSB:7n5q, PDBe:7n5q, PDBj:7n5q
PDBsum7n5q
PubMed35999236
UniProtP01899|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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