Structure of PDB 7mli Chain F

Receptor sequence
>7mliF (length=346) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLI
REVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHIA
REGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKF
EYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQ
LQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDS
FYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLID
GREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD
3D structure
PDB7mli Structural and mechanistic basis of reiterative transcription initiation.
ChainF
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna F D323 E324 D246 E247
BS02 dna F D79 V81 R82 L85 G89 N191 R193 L194 S197 K200 F209 K226 E228 R231 F233 K234 S236 T237 Y238 T240 W241 D2 V4 R5 L8 G12 N114 R116 L117 S120 K123 F132 K149 E151 R154 F156 K157 S159 T160 Y161 T163 W164
BS03 MG F A292 G296 W299 A215 G219 W222
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7mli, PDBe:7mli, PDBj:7mli
PDBsum7mli
PubMed35082149
UniProtQ5SKW1

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