Structure of PDB 7k09 Chain F

Receptor sequence
>7k09F (length=195) Species: 132473 (Streptomyces alboniger) [Search protein sequence]
KPTVRLATRDDVPRAVRTLAAAFADYPATRHTVDPDRHIERVTELQELFL
TRVGLDIGKVWVADDGAAVAVWTTPESVEAGAVFAEIGPRMAELSGSRLA
AQQQMEGLLAPHRPKEPAWFLATVGVSPDHQGKGLGSAVVLPGVEAAERA
GVPAFLETSAPRNLPFYERLGFTVTADVEVPEGPRTWCMTRKPGA
3D structure
PDB7k09 Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.
ChainF
Resolution2.313 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO F F27 Y30 V128 V130 Q135 G136 G138 G140 S141 E161 R166 N167 F170 Y171 R173 F23 Y26 V124 V126 Q131 G132 G134 G136 S137 E157 R162 N163 F166 Y167 R169
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:7k09, PDBe:7k09, PDBj:7k09
PDBsum7k09
PubMed33664348
UniProtP13249|PUAC_STRAD Puromycin N-acetyltransferase (Gene Name=pac)

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