Structure of PDB 7f7i Chain F

Receptor sequence
>7f7iF (length=182) Species: 10116 (Rattus norvegicus) [Search protein sequence]
HYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYH
FVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVS
ANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLE
QEFTECFSAIVEGDSFEEIYHKVKRVIEDLSG
3D structure
PDB7f7i Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
ChainF
Resolution2.595 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F Q603 S606 Q72 S75
BS02 peptide F D545 D549 S561 Y580 E600 G602 Y604 G610 T611 D629 D14 D18 S30 Y49 E69 G71 Y73 G79 T80 D98
External links
PDB RCSB:7f7i, PDBe:7f7i, PDBj:7f7i
PDBsum7f7i
PubMed34458841
UniProtP31016|DLG4_RAT Disks large homolog 4 (Gene Name=Dlg4)

[Back to BioLiP]