Structure of PDB 7f75 Chain F

Receptor sequence
>7f75F (length=272) Species: 1423 (Bacillus subtilis) [Search protein sequence]
DPVRMYLKEIGRVNLLSAKEEIAYAQKIEEGDEESKRRLAEANLRLVVSI
AKRYVGRGMLFLDLIQEGNMGLMKAVEKFDYRKGYKFSTYATWWIRQAIT
RAIADQARTIRIPVHMVETINKLIRVQRQLLQDLGREPTPEEIAEDMDLT
PEKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDQEATSPSDHAAYELL
KEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGKVFGVTRERIRQI
EAKALRKLRHPSRSKRLKDFLE
3D structure
PDB7f75 Structural basis of transcription activation by the global regulator Spx.
ChainF
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F V102 R103 L106 A141 R144 R181 K185 S187 T188 Y189 Q196 R200 R210 T342 R345 V3 R4 L7 A42 R45 R82 K86 S88 T89 Y90 Q97 R101 R111 T243 R246
BS02 dna F Y153 G155 R156 R224 I270 F281 L332 E333 Y54 G56 R57 R125 I171 F182 L233 E234
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation
GO:0006355 regulation of DNA-templated transcription
GO:0010468 regulation of gene expression
GO:2000142 regulation of DNA-templated transcription initiation
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:7f75, PDBe:7f75, PDBj:7f75
PDBsum7f75
PubMed34530448
UniProtP06224|SIGA_BACSU RNA polymerase sigma factor SigA (Gene Name=sigA)

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