Structure of PDB 7eby Chain F

Receptor sequence

>7ebyF (length=761) Species: 1744839 (Cupriavidus sp. P4-10-C)

TDRYAAPGLEKPASILIDRWGVPHIYAGTLYDAFYAQGFIAARDRLWQID
LWRKRGLGEMARDFGPAYVDGDRMARAVLYRGDMYREWLAYGSDAKRVAE
AFVAGVNAYVALTEAQPELLPREFKQLGYKPSRWRAEDIVRIRHHGLTLN
FTGEVDRATLYCQAKEQAARADWLRRELDPPITPTLPEGLDPCAVPAAAL
KKAYTLATAAANFPKEAWSNNWVIAGSRTSTGRPILANDPHRAHGAPSLR
YVSHLNAPGLSVIGAGEPFLPGISIGHNGTIAFGLTRFYMDQEDLYVYET
DPAQPKSYRYRGRWEPMETITEKITVRGEAEPRTVTIDFTRHGPVLHADD
ASHRAWALRAAWLDTGMAPYFGSMDYMRATNWDQFRAAMNRWGAPGENQV
YADRNGNIGWIPGGLTVIRPNWDGLFPVPGDGRYEWAGYRNMDELPWAYN
PSTGHIVTANENNIPPDHPAAKLGVGYEWSDSSRARRLKSLVAAAPVSSL
RDSIAWQNDTVSLPAQRTLAVMRTVGNAGAAASLLQDPQVQRAVALLRGW
DGNVRADSVPAALFEIWFSNHLRQAVVRAALPEDAAKLVGAGDAARVLAV
LEQPDTWMPTARRDEVMLTSLKAAMAELERRSPSPEKLATWGTLHRAIFR
HPLANIVDDATRAQYNVDAGGIGGSAFTPMNTSYRNSDYHLTAGASFRMV
LDVGNWDQGRVVNTPGQSGDPGNSHYRDLAPIWAKGQTFPLVYSRKAVER
AAEKRIELTPR

3D structure

• PDB: 7eby Protein Engineering of d-Succinylase from Cupriavidus sp. for d-Amino Acid Synthesis and the Structural Implications.
• Chain: F
• Resolution: 2.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CO3	F	S282 H304 R350 N523	S219 H241 R287 N460
BS02	CO3	F	R305 R313 L348 Y433 E460	R242 R250 L285 Y370 E397
BS03	CA	F	N165 E169 D354 E356 D357 G487	N150 E154 D291 E293 D294 G424

Gene Ontology

Molecular Function

• GO:0016787 hydrolase activity
• GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

Biological Process

• GO:0017000 antibiotic biosynthetic process

External links

• PDB: RCSB:7eby, PDBe:7eby, PDBj:7eby
• PDBsum: 7eby
• UniProt: A0A0N7KZ58