Structure of PDB 7ea5 Chain F

Receptor sequence
>7ea5F (length=78) Species: 8355 (Xenopus laevis) [Search protein sequence]
DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYT
EHAKRKTVTAMDVVYALKRQGRTLYGFG
3D structure
PDB7ea5 Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
ChainF
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F R35 R45 I46 K79 T80 R12 R22 I23 K56 T57
BS02 dna F R36 R45 R13 R22
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin

View graph for
Molecular Function
External links
PDB RCSB:7ea5, PDBe:7ea5, PDBj:7ea5
PDBsum7ea5
PubMed33972509
UniProtP62799|H4_XENLA Histone H4

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