Structure of PDB 7dcs Chain F

Receptor sequence
>7dcsF (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
VPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHN
NMASFVRQLNMYGFRKVVHDTEFQHPCFLRGQEQLLENIKRKV
3D structure
PDB7dcs Structures of heat shock factor trimers bound to DNA.
ChainF
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F F18 F61 K62 H63 S68 R71 Q72 Y76 R117 F4 F47 K48 H49 S54 R57 Q58 Y62 R91
BS02 dna F K62 R71 N74 R79 K80 K48 R57 N60 R65 K66
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7dcs, PDBe:7dcs, PDBj:7dcs
PDBsum7dcs
PubMed34458700
UniProtQ00613|HSF1_HUMAN Heat shock factor protein 1 (Gene Name=HSF1)

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