Structure of PDB 7ccq Chain F

Receptor sequence
>7ccqF (length=79) Species: 9606 (Homo sapiens) [Search protein sequence]
RDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTY
TEHAKRKTVTAMDVVYALKRQGRTLYGFG
3D structure
PDB7ccq Structural basis for nucleosome-mediated inhibition of cGAS activity.
ChainF
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna F R45 I46 S47 G48 R78 K79 R23 I24 S25 G26 R56 K57
BS02 dna F T30 P32 R36 R45 T8 P10 R14 R23
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:7ccq, PDBe:7ccq, PDBj:7ccq
PDBsum7ccq
PubMed33051594
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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