Structure of PDB 7ask Chain F

Receptor sequence
>7askF (length=1523) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]
MSSRYRELIAIFGEFLEENDFHVRISMDRVGEVKTLFSAKTIPVESETEA
AIEVVTIEAARRRDALRRTCNAVLRTRHSDQHVDVGTIVADEEERLAWKF
LIGALAAKNSEILPVVEAELLLAAVEYHYATARPELCDMFVHLSASEMFF
IDGDSLFMAALSPQSVDWDLIQPLHVIYNAQKLLYDMHCRGARFHVVFFD
SLLWIWESAPAKLFMRENLRKTLMSLSENDAKVGLSISNFSSYYSEAFET
YVKQWEPEFILMSDGEQLGRLNPLQAFFVRPSAANNTHDSRRKANYTDAD
EANPYRLRRQYRSIVEDEAVGDKSDDDAGGNSANNKTAGAKKVNKEHAGQ
RNKKERSKEDEIRERSNVIAATATVAEWHKQMNHLLHAVDMSHGRTTNRD
RDESINTIMAAIKRLSQEKFGKNFDPGYTLGGSTNTAVPLKLEMWRLLVA
ASQLREVEFAFAMEDPALKDSKGASKKKDSKSEYKMLYGFHVINQFVERE
AVKGNHWGQLDPLRKAKPDMTIVEARSYLRWVYLSFVEMHIQLKLKCRVV
KLQLENWRAERERARLAQESPKIALGIPLFLYCHHHVLAVIRDEGPRMSS
EDIDTVRSALKHFDLPDSYYNKLDQCIARWQNMTLGTLLPSLLPQDKQLF
ETPEMLQLIHMGHLLERPFVREHDYRVAFNPDNWQRELLDIVDGRGSAVV
CAPTSAGKTFISYYCMYKALRRTNKKVVVYLAPARALINQAVADVCARYG
SKKYKNPGRYIYGALGGADYHQFHDSCQVLLTVPETFETMLLSPKYTDWV
ELIDYVILDEIHSMESNGNGDVWERILALLPCPFVALSATLGETQQLCSW
LNRVQGRLKEQTEEMSGKMRDFEVHLLPSEGKSIQRWNDIKKYIYLPPPG
AALTQKKIKAQYNNCYIRDLHPLSILTADQLQRGFPPDISLVPSEVVSLF
EKMHSKFNEVVWPNYSSLQLAKTLRAQLMLIEPSKYFEAETYITQERARQ
YEAEVKNAFAYWAYLGHEGCELPENLVEEDLDDFSASMNMAVESILRTFA
QKLNEDEALLERHAADGMEKKKRMLLRQQHLQLLQQQEQENEPNQEESME
QKSEEQGGAQEEEQEKETVGSVSFPGSRQFIREHILNVLRELIARDMGPT
IVFSFESEDCGDLVKYVVEQLEEAESRYRKTNEFALYKARIERAAAAQEA
RRKQRESTLKQKRLTTGDDGDVEVADRDMSDGEGEDELFVVPDVLPEFTF
IGEKCTVEPEVVDSLMEDCEKEGEDLLLRALQRGIGMHHAGVKGKLRAHV
ERLFRGRHCGVIFSTETLALGIHSPCRSVVLAGDHILLNPTQFRQMMGRA
GRRGLDYLGHLVFLGITMRRIKRLMTSSMTVIKGNVQMDPISNLRLLQLY
DFNTLRHLKNEAGWKTHVLKLAERLFVNPLFFQGRNSVAGGNMEGFTVEW
LQMLLGYFQREGLHFSDHASSLGSILQDAMYVFREAHVGNEGFSFIRMLT
SGVFDKAHYSPLYDKKLNSGVLD
3D structure
PDB7ask Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
ChainF
Resolution4.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG F K1052 T1053 K708 T709
BS02 ADP F P1025 A1050 G1051 K1052 F1054 R1697 P681 A706 G707 K708 F710 R1353
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:7ask, PDBe:7ask, PDBj:7ask
PDBsum7ask
PubMed33357443
UniProtQ4E5Z1

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