Structure of PDB 6zi7 Chain F

Receptor sequence
>6zi7F (length=398) Species: 1890 (Streptomyces antibioticus) [Search protein sequence]
PADAVPAYPFSLPHALDLDPHYAELRRDEPVSRVRLPYGEGTAWLVTRMS
DARIVLGDSRFSTAAATDPATPRMFPTPPEPDGVLAQDPPDHTRLRRLVG
KAFTARRVEEMRPRVRSLVDSLLDDMVAHGSPADLVEFLAVPFPVAVICE
LLGVPLEDRDLFRTFSDAMLSSTRLTAAEIQRVQQDFMVYMDGLVAQRRD
APTEDLLGALALATDNDDHLTKGEIVNMGVSLLIAGHETSVNQITNLVHL
LLTERKRYESLVADPALVPAAVEEMLRYTPLVSAGSFVRVATEDVELSTV
TVRAGEPCVVHFASANRDEEVFDHADELDFHRERNPHIAFGHGAHHCIGA
QLGRLELQEALSALVRRFPTLDLAEPVAGLKWKQGMLIRGLERQIVSW
3D structure
PDB6zi7 Dissecting the Cytochrome P450 OleP Substrate Specificity: Evidence for a Preferential Substrate.
ChainF
Resolution2.28 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S180 A244 E247 T248 S249 S292 C356 I357 G358 E365 I397
Catalytic site (residue number reindexed from 1) S171 A235 E238 T239 S240 S283 C347 I348 G349 E356 I388
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEM F V93 L94 H101 R105 A244 G245 T248 Q252 L290 R298 F321 A348 F349 H354 C356 I357 G358 V84 L85 H92 R96 A235 G236 T239 Q243 L281 R289 F312 A339 F340 H345 C347 I348 G349
BS02 QR8 F F84 L94 F75 L85
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6zi7, PDBe:6zi7, PDBj:6zi7
PDBsum6zi7
PubMed33036250
UniProtQ59819

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