Structure of PDB 6y32 Chain F

Receptor sequence
>6y32F (length=304) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSLSREDMESVLDKMRDHLIAKNVAADIAVQLCESVANKLEGFSTVTST
VKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYVVTFCGVNGVGKSTN
LAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGR
TMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTA
LAKLITVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDG
IVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAA
LMKA
3D structure
PDB6y32 Structural and Functional Impact of SRP54 Mutations Causing Severe Congenital Neutropenia.
ChainF
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP F N427 R458 N93 R124
BS02 GNP F G428 G430 K431 S432 T433 N434 R458 G523 K589 D591 G615 G617 Q618 G94 G96 K97 S98 T99 N100 R124 G189 K255 D257 G281 G283 Q284
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane

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Molecular Function
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Biological Process
External links
PDB RCSB:6y32, PDBe:6y32, PDBj:6y32
PDBsum6y32
PubMed33053321
UniProtP08240|SRPRA_HUMAN Signal recognition particle receptor subunit alpha (Gene Name=SRPRA)

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