Structure of PDB 6w6j Chain F

Receptor sequence
>6w6jF (length=605) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMFEERLKAVLDDIK
NSAGQIITFIDELHTIVNMIKPMLARGELRLVGATTLDEYRKHIEKDAAL
ERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDR
YITARFLPDKAIDLVDEAASRLRMEIDSRPVEIDEVERLVRRLEIEEMAL
SKEEDEASAERLAKLRSELADQKEKLAELTTRWQNEKNAKEEVGPDDIAD
VVSAWTGIPAGRLLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSR
AGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYG
EKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFD
VLLQVLDEGRLTDGHGRTVDFRNTILILTSNLGSGGSAEQVLAAVRATFK
PEFINRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAK
RWLAQRGFDPVYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSP
DADSL
3D structure
PDB6w6j Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
ChainF
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS F R571 V572 I573 T609 G610 V611 G612 K613 T614 E615 A804 R805 R331 V332 I333 T369 G370 V371 G372 K373 T374 E375 A564 R565
BS02 ADP F D178 P179 T213 A214 I350 D20 P21 T55 A56 I170
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6j, PDBe:6w6j, PDBj:6w6j
PDBsum6w6j
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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