Structure of PDB 6w6g Chain F

Receptor sequence
>6w6gF (length=531) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMFEERLKAVLDDIK
NSAGQIITFIDELHTIVNMIKPMLARGELRLVGATTLDEYRKHIEKDAAL
ERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDR
YITARFLPDKAIDLVDEAASRLRMEIDKEEVGPDDIADVVSAWTGIPAGR
LLEGETAKLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGA
FMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYGEKHTVARLIGQL
TEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNT
ILILTSNLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRI
VDIQLAQLGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRRLVQQA
IGDQLAKMLLAGQVHDGDTVPVNVSPDADSL
3D structure
PDB6w6g Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
ChainF
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AGS F R571 V572 I573 T609 G612 K613 T614 E615 A804 R805 R269 V270 I271 T307 G310 K311 T312 E313 A490 R491
BS02 ADP F V180 P208 G209 V210 G211 K212 T213 I350 D389 V22 P50 G51 V52 G53 K54 T55 I170 D209
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6g, PDBe:6w6g, PDBj:6w6g
PDBsum6w6g
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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