Structure of PDB 6vke Chain F

Receptor sequence

>6vkeF (length=432) Species: 11259,11676 [Search protein sequence]

NITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIDAKVKLIKQELD
KYKNAVTELQLLMQSTPATFLGFLLGVGSAIASGVAVCKVLHLEGEVNKI
KSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPILSNIETVIEFQ
QKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLM
SNNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTT
NTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLT
LPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTA
SNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPI
INFYDPLVFPSDEFDASISQVNEKINQSLAFI

3D structure

PDB

6vke Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus.

Chain

Resolution

2.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand