Structure of PDB 6v0a Chain F

Receptor sequence

>6v0aF (length=441) Species: 398767 (Trichlorobacter lovleyi SZ)

IPDGTIDPAVWGKNYPEEYQTWKDTALPTPEGKSKYKKGNDGGKVYDKLS
EYPFIALLFNGWGFGIEYNEPRGHVYMMKDQKEIDPSRLKGGGACLTCKT
PYAPQLAQKQGVTYFSQSYADAVNQIPEHQEMGVACIDCHNNKDMGLKIS
RGFTLVKALDKMGVDQTLTNQDKRSLVCAQCHVTYTIPKDANMKSQDVFF
PWDESKWGKISIENIIKKMRSDKSYGEWTQAVTGFKMAYIRHPEFEMYSN
QSVHWMAGVSCADCHMPYTKVGSKISDHRIMSPLKNDFKGCKQCHSESSE
WLKNQVITIQDRAASQYIRSGYALATVAKLFEMTHKQQAAGKQIDQKMYD
QAKFYYEEGFYRNLFFGAENSIGFHNPTEAMRILGDATMYAGKADGLLRQ
ALTKAGVDVPVKIDLELSKYTNNRGAKKLMFKPEQELKDPY

3D structure

• PDB: 6v0a Cytochromecnitrite reductase from the bacteriumGeobacter lovleyirepresents a new NrfA subclass.
• Chain: F
• Resolution: 2.55 Å

Enzymatic activity

• Enzyme Commision number: 1.7.2.2: nitrite reductase (cytochrome; ammonia-forming).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEC	F	N103 Q115 I118 R122 C129 C132 K133 C217 H218 Y221 H278 N407	N69 Q81 I84 R88 C95 C98 K99 C181 H182 Y185 H242 N370
BS02	HEC	F	Y49 E52 W56 A170 C171 C174 H175 M180 L182 R210 M302 K311 I312 S313 H315	Y15 E18 W22 A135 C136 C139 H140 M145 L147 R174 M266 K274 I275 S276 H278
BS03	HEC	F	P105 R106 G107 H108 Y110 M111 D114 K133 C214 C217 H218 H301 I317	P71 R72 G73 H74 Y76 M77 D80 K99 C178 C181 H182 H265 I280
BS04	HEC	F	S68 K71 H218 E280 Y284 H290 S296 C297 C300 H301 S319 P320 L321 Q347 N407 F411 H412	S34 K37 H182 E244 Y248 H254 S260 C261 C264 H265 S282 P283 L284 Q310 N370 F374 H375
BS05	HEC	F	V289 H290 P320 G327 C328 C331 H332 F411	V253 H254 P283 G290 C291 C294 H295 F374

Gene Ontology

Molecular Function

• GO:0042279 nitrite reductase (cytochrome, ammonia-forming) activity

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:6v0a, PDBe:6v0a, PDBj:6v0a
• PDBsum: 6v0a
• PubMed: 32518164
• UniProt: B3E641