Structure of PDB 6u0u Chain F

Receptor sequence
>6u0uF (length=429) Species: 5911 (Tetrahymena thermophila) [Search protein sequence]
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPAFNTFFSETGAGK
HVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTI
GKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVD
YGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNEAIY
DICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNLV
PYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDPRHG
KYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVG
EGMEEGEFSEAREDLAALEKDYEEVGIET
3D structure
PDB6u0u Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins.
ChainF
Resolution4.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP F G10 Q11 G12 E71 D98 A99 S140 G143 G144 T145 T179 N206 Y224 N228 G10 Q11 G12 E61 D88 A89 S130 G133 G134 T135 T169 N196 Y214 N218
BS02 GDP F L248 E254 L238 E244
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Biological Process
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Cellular Component
External links
PDB RCSB:6u0u, PDBe:6u0u, PDBj:6u0u
PDBsum6u0u
PubMed31527277
UniProtP41351|TBA_TETTH Tubulin alpha chain

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