Structure of PDB 6u0t Chain F

Receptor sequence
>6u0tF (length=429) Species: 5911 (Tetrahymena thermophila) [Search protein sequence]
MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPAFNTFFSETGAGK
HVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTI
GKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVD
YGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNEAIY
DICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNLV
PYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDPRHG
KYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQPP
TVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVG
EGMEEGEFSEAREDLAALEKDYEEVGIET
3D structure
PDB6u0t Tubulin lattice in cilia is in a stressed form regulated by microtubule inner proteins.
ChainF
Resolution4.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP F Q11 G12 Q15 E71 A99 A100 G143 G144 T145 T179 N206 Y224 N228 Q11 G12 Q15 E61 A89 A90 G133 G134 T135 T169 N196 Y214 N218
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Cellular Component
External links
PDB RCSB:6u0t, PDBe:6u0t, PDBj:6u0t
PDBsum6u0t
PubMed31527277
UniProtP41351|TBA_TETTH Tubulin alpha chain

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