Structure of PDB 6u0p Chain F

Receptor sequence
>6u0pF (length=579) [Search protein sequence]
PDIRVPVLIVGGGPAGLTAALALSRYGVPHLLVNRHHGTAHTPRAHLLNQ
RTGEIFRDLGIADRVEAHATPGHLMANHVFMSTFAGPEVARIGAYGNGPD
RIGEYRAASPSGLCNLPQHLLEPLLVEAVQEACVGQLRFGHEFVSLEQDE
HGVTSRITDRRTGRDYTVRSDYLIGADGARSRVLAQLGIALDGATGIARA
VTTWFEADLSRYSAHRPALLYMGAVPGSPPADGRVFVSLRPWTEWLHLTF
PPPTADVDVEDHEAVRAGIRESIGDPTVDVTIKNVSAWEVNSAVAPRYAS
GRVFCVGDAVHQNPPTNGLGLNSAVADSFNLCWKLKLALEGLAGPGLLDT
YHDERQPVGRQIVDRAFRSMVDLIGIPQALGFTEGQSPEEQWRLLDTLHE
DTEEARQRRAALAAATAAIHGQANAHGVELGYRYRTGALVPDGTPEPADE
RDPELYYRATTWPGARLPHAWLENGRHRCSTLDVTGRGRFTLLTGPGGEP
WRDAARDAALDTGVEVAVLPIGAGGGPRDPYGTWAELREVEESGAVLVRP
DGHVAWRARDHGHAKELPEVMARVLHQPD
3D structure
PDB6u0p Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations.
ChainF
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD F G19 G21 P22 A23 N42 R43 H44 R52 A53 Q126 F151 D185 G186 W296 G315 D316 P323 G11 G13 P14 A15 N34 R35 H36 R44 A45 Q118 F143 D177 G178 W288 G307 D308 P315
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004497 monooxygenase activity
GO:0016491 oxidoreductase activity
GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0071949 FAD binding

View graph for
Molecular Function
External links
PDB RCSB:6u0p, PDBe:6u0p, PDBj:6u0p
PDBsum6u0p
PubMed32111738
UniProtW0C4C9

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