Structure of PDB 6tz8 Chain F

Receptor sequence
>6tz8F (length=111) Species: 235443 (Cryptococcus neoformans var. grubii H99) [Search protein sequence]
GVTVENIKEGNGVDKPVKGDNVTIHYVGTLLDGSKFDSSRDRGTPFVCRI
GQGQVIRGWDEGVPQLSLGEKANLICTPDYAYGARGFPPVIPPNSTLKFE
VELLKVNSKRA
3D structure
PDB6tz8 Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents.
ChainF
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FK5 F Y27 D38 R43 F47 V56 I57 W60 Y83 F88 F100 Y26 D37 R42 F46 V55 I56 W59 Y82 F87 F99
Gene Ontology
Molecular Function
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005515 protein binding
Biological Process
GO:0000413 protein peptidyl-prolyl isomerization
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tz8, PDBe:6tz8, PDBj:6tz8
PDBsum6tz8
PubMed31537789
UniProtO94746|FKBP_CRYNH FK506-binding protein 1 (Gene Name=FRR1)

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