Structure of PDB 6s1c Chain F

Receptor sequence
>6s1cF (length=299) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SINLHSAPEYDPSYKLIQLTPELLDIIQDPVQNHQLRFKSLDKDKSEVVL
CSHDKTWVLKQRKHSNTVLLMREFVPEQPITFDETLLFGLSKPYMDVVGF
AKTESEFETRETHGELNLNSVIGTLEELLENSPCSALEGISKWHKIGGSC
ILSQDFLFKALHVLLMSAMAESLLRIPFIAQWYGIQALRKYVSGISMPID
EFLIKWKSLFPPFFPCDIDIDMLRGYHFKKTVQYIAKSTLPMDPKERFKV
LFRLQSQWDLEDIKPLIEELNSRGMKIDSFIMKYARRKRLGKKTVVTSR
3D structure
PDB6s1c Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.
ChainF
Resolution6.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide F P13 K16 K44 L60 K61 Q62 R63 S66 N67 F108 P12 K15 K43 L59 K60 Q61 R62 S65 N66 F107
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006260 DNA replication
GO:0007064 mitotic sister chromatid cohesion
GO:0034088 maintenance of mitotic sister chromatid cohesion
GO:0034398 telomere tethering at nuclear periphery
GO:0035753 maintenance of DNA trinucleotide repeats
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0031390 Ctf18 RFC-like complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:6s1c, PDBe:6s1c, PDBj:6s1c
PDBsum6s1c
PubMed32585006
UniProtP25559|DCC1_YEAST Sister chromatid cohesion protein DCC1 (Gene Name=DCC1)

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