Structure of PDB 6rpb Chain F

Receptor sequence
>6rpbF (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWI
EQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYGCD
VGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAAHV
AEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEATLR
CWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSG
QEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB6rpb TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
ChainF
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide F Y7 M45 E63 K66 V67 H70 T73 V76 D77 T80 Y84 Y99 Y116 T143 K146 W147 V152 L156 Y159 W167 Y171 Y7 M43 E61 K64 V65 H68 T71 V74 D75 T78 Y82 Y97 Y114 T141 K144 W145 V150 L154 Y157 W165 Y169
External links
PDB RCSB:6rpb, PDBe:6rpb, PDBj:6rpb
PDBsum6rpb
PubMed32102902
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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