Structure of PDB 6rft Chain F

Receptor sequence
>6rftF (length=405) Species: 36809 (Mycobacteroides abscessus) [Search protein sequence]
ELTLRTIADEDDYESYMASAYSVFLRDPQKDEIEVNRKFTELDRMIGFHD
GKKWVATTGAFSRHVVLPGGAVVPVAAVTAVTVSPTHRRRGLLTTMMRHQ
LADIRSRGESLAMLFASEALIYGRFGYGVATESAELSGQVRELAFRPTVD
LGDGTLEEVSAETFLASAPAIYDAVIPGLPGQMSRTPEWWASWTLDSEEL
QKESGKVRFVLHYESDGTASGFAIYRPKPGWPNAELHVQEVLGTNPRSYA
RTWRYLLDMDLVRKIKYHGASVQEELRYLVANHPSLECVVSDAIQVRLVD
IPRALAQRRYAADVDVVLEVTDDFLPENSGRYRLRGGLDHASCEITTDDA
DIALTVRDLGSVYMGGVSLQVLASAGLVTELRAGAVQRAATAFGWPVAPS
APDDF
3D structure
PDB6rft Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacterium abscessus.
ChainF
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO F V25 F26 V85 R90 R91 G93 L95 T96 I123 R126 V23 F24 V83 R88 R89 G91 L93 T94 I121 R124
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0034069 aminoglycoside N-acetyltransferase activity
Biological Process
GO:0030649 aminoglycoside antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6rft, PDBe:6rft, PDBj:6rft
PDBsum6rft
PubMed31254444
UniProtA0A1M9A4M7

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