Structure of PDB 6ov8 Chain F

Receptor sequence
>6ov8F (length=427) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARK
IDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVVWPDLDDAQRQEL
DNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGE
DLREQGYMGLHTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFD
SGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKRVKLFLCCADN
LISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEMII
DAATLTGAAKTALGNDYHALFSFDDALAGRLLASAAQENEPFWRLPLAEF
HRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSAT
YRKAPVEQWSAGATGLGVRTIANLLTA
3D structure
PDB6ov8 Comparison of metal-bound and unbound structures of aminopeptidase B proteins from Escherichia coli and Yersinia pestis.
ChainF
Resolution2.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.11.23: PepB aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN F K195 D200 D218 E279 K195 D200 D218 E279
BS02 MN F D200 K207 D277 E279 D200 K207 D277 E279
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0030145 manganese ion binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0019538 protein metabolic process
GO:0043171 peptide catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:6ov8, PDBe:6ov8, PDBj:6ov8
PDBsum6ov8
PubMed32306515
UniProtP37095|PEPB_ECOLI Peptidase B (Gene Name=pepB)

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