Structure of PDB 6o20 Chain F

Receptor sequence

>6o20F (length=148) Species: 9913 (Bos taurus) [Search protein sequence]

ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQD
MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI
SAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK

3D structure

PDB

6o20 Structural insight into TRPV5 channel function and modulation.

Chain

Resolution

3.3 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	F	M109 L112 E114 E120 E123 M124 E127 F141 M144 M145 K148	M109 L112 E114 E120 E123 M124 E127 F141 M144 M145 K148
BS02	CA	F	D129 D131 D133 Q135 V136 N137	D129 D131 D133 Q135 V136 N137
BS03	CA	F	D93 D95 N97 Y99 I100 E104	D93 D95 N97 Y99 I100 E104
BS04	CA	F	G25 T26 E31	G25 T26 E31
BS05	CA	F	D56 D58 N60 T62 E67	D56 D58 N60 T62 E67

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0046872	metal ion binding

	Biological Process
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0060315	negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity

	Cellular Component
GO:0000922	spindle pole
GO:0005737	cytoplasm
GO:0005819	spindle
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0032991	protein-containing complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:6o20, PDBe:6o20, PDBj:6o20
PDBsum	6o20
PubMed	30975749
UniProt	P62157\|CALM_BOVIN Calmodulin (Gene Name=CALM)

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