Structure of PDB 6ncz Chain F

Receptor sequence
>6nczF (length=589) Species: 1150298 (Fusicatenibacter saccharivorans) [Search protein sequence]
MSDIHLEDYTEQYETGFATVDTMIFEGGRREELLNGGWHYAVDQYDTCLR
QKWYKERYRDEKGFTVPIDYSFDEWPVMQLPCSWNTIDPMYLLYEGSMVF
TRKFSYIAEREETVFLKVGAANYLCRVFLNGKYVGMHRGGSTPAFWNITE
YLKAENRIVLAVDGTRRPEQVPTENTDWFNYCGVYRDIALIRVPKCHIKT
FKIALVPDGTFGHVMAKVTLSEKITAKAELVIEELGVSRKIQLENGAGEV
VFDAKPELWTPEKPKLYDVKVTCGTDTVSDRVGFREIRVNGRDILLNGEP
VFLRGISCHEDSVENGKGLTREERIENIRIAKELGCNFMRLAHYPHNEEM
AKLADELGLLLWEEIPVYWAIRFEREKTYEDAQNQLRELINRDWNRASVI
IWSVGNENADTDERLKFMSVLAECAHREDETRMVSAACLVNAAKNKIEDR
LMEYLDIIGINEYCGWYTPDFAMLPALMENSQPDKPVIVTEFGADALPHH
HGTISDKGTEECQADVYEKQIATLRNIDYIKGMTPWILYDFRCPRRTSLI
QKYYNRKGLLSEDKKYRKPAFYVLQKFYEELKRKEQENL
3D structure
PDB6ncz Selecting a Single Stereocenter: The Molecular Nuances That Differentiate beta-Hexuronidases in the Human Gut Microbiome.
ChainF
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.31: beta-glucuronidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FYJ F D177 H343 Y368 E407 N461 Y463 Y467 E491 W536 R546 N555 K557 D177 H343 Y368 E407 N461 Y463 Y467 E491 W536 R546 N555 K557
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004565 beta-galactosidase activity
GO:0004566 beta-glucuronidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0030246 carbohydrate binding
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6ncz, PDBe:6ncz, PDBj:6ncz
PDBsum6ncz
PubMed30729778
UniProtA0A174EHD1

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