Structure of PDB 6mus Chain F

Receptor sequence

>6musF (length=377) Species: 342948 (Thermococcus onnurineus) [Search protein sequence]

MTERTLKVLSPLHIGTGNELTPVDIYPRENIIHVLDTERLVNDLMNLGEL
NEILALLKNPPAYIWKGYIEEFHLDPSDYSIYTLKIHGRKSMQIKEFIKL
NGRPYIPGSSLKGAIRTAVLYKALKECDARAVMRVVSKVNGDVARDIGRD
VLDYYMSFLSRKRADDLLEAIVFGMEPDRRSKIRYEPKRDPMKALIVRDS
KPVGRKHLAVYHVEVIGNPQPIPIWVEAIEPGAATDVEIHVDTEALRLNA
DYFNGLLWECLKERGEPGEVFEDFLWEAVDEFYTAVMKYETIEVQKFSQV
RSFYASLEDHSGHVLRLGWGSGWLAMTIGLLLVEKGYKWENVRKKLGLGK
KGSGFSREFPKTRRLADGMPMGWVVLE

3D structure

PDB

6mus Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.

Chain

Resolution

3.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	F	G15 T16 G17 S115 S116 K118 G119 A120 R122 Y199 P201 Q234 R334 L335 G336 W337 S339 W341 M344 L366 K368 K369 K381 T382 R384	G15 T16 G17 S109 S110 K112 G113 A114 R116 Y185 P187 Q220 R316 L317 G318 W319 S321 W323 M326 L348 K350 K351 K361 T362 R364
BS02	rna	F	R95 S97 R198 I236	R89 S91 R184 I222

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Biological Process
GO:0051607	defense response to virus

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Molecular Function

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Biological Process

External links

PDB	RCSB:6mus, PDBe:6mus, PDBj:6mus
PDBsum	6mus
PubMed	30503773
UniProt	B6YWC2

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