Structure of PDB 6k1h Chain F

Receptor sequence
>6k1hF (length=273) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence]
KKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCFSMVPAIRRLYPENNEA
RKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDGAINGIKVG
LMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHV
NIPLVVSRITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVN
PLWIIVGFFVIGIAGYACGLLGL
3D structure
PDB6k1h Structure of the mannose transporter of the bacterial phosphotransferase system.
ChainF
Resolution3.52 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MAN F Q32 W35 Q78 D123 W127 Q19 W22 Q65 D110 W114
Gene Ontology
Molecular Function
GO:0022870 protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
Biological Process
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0015761 mannose transmembrane transport
GO:0015764 N-acetylglucosamine transport
GO:0098708 D-glucose import across plasma membrane
GO:1990539 fructose import across plasma membrane
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:1902495 transmembrane transporter complex

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External links
PDB RCSB:6k1h, PDBe:6k1h, PDBj:6k1h
PDBsum6k1h
PubMed31209249
UniProtP69805|PTND_ECOLI PTS system mannose-specific EIID component (Gene Name=manZ)

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