Structure of PDB 6k0r Chain F

Receptor sequence
>6k0rF (length=307) Species: 9606 (Homo sapiens) [Search protein sequence]
GAHSHIRGLGLDDALEPRASQGMVGQLAARRAAGVVLEMIREGKIAGRAV
LIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAF
RRSIGVRIHTVSLHEIDVINSRTEIKSEVREQINAKVAEWREEGKAEIIP
GVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSP
HGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRI
GLETSLRYAIQLITAASLVCRKRTEVQVDDIKRVYSLFLDESRSTQYMKE
YQDAFLF
3D structure
PDB6k0r Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals.
ChainF
Resolution2.502 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CUU F H25 H27 M46 V47 G80 G82 K83 T84 Y362 H3 H5 M23 V24 G57 G59 K60 T61 Y219
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:6k0r, PDBe:6k0r, PDBj:6k0r
PDBsum6k0r
PubMed32376767
UniProtQ9Y230|RUVB2_HUMAN RuvB-like 2 (Gene Name=RUVBL2)

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