Structure of PDB 6jmt Chain F

Receptor sequence
>6jmtF (length=346) Species: 10090 (Mus musculus) [Search protein sequence]
LRSSDVCADCNGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHT
AWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKA
EFIRAKYQMLAFVHRLPCREDDSVTAKDLSKQLHSSVRTGNLETCLRLLS
LGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPV
DYARQGGHHELAERLIEIQYELTDRLAFYLCGRKPDHKSGQHFLIPQRAD
AALDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNH
SVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
3D structure
PDB6jmt GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
ChainF
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide F A266 K267 K269 L270 L277 L281 S324 T326 R327 G330 F337 D348 A262 K263 K265 L266 L273 L277 S312 T314 R315 G318 F325 D336
BS02 ZN F C11 C14 C31 C34 C7 C10 C27 C30
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
Biological Process
GO:0007420 brain development
GO:0032012 regulation of ARF protein signal transduction

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6jmt, PDBe:6jmt, PDBj:6jmt
PDBsum6jmt
PubMed32780989
UniProtQ9JLQ2|GIT2_MOUSE ARF GTPase-activating protein GIT2 (Gene Name=Git2)

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