Structure of PDB 6jma Chain F

Receptor sequence
>6jmaF (length=87) Species: 8355 (Xenopus laevis) [Search protein sequence]
KRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENV
IRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB6jma Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
ChainF
Resolution6.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F R45 I46 S47 G48 K79 T80 R30 I31 S32 G33 K64 T65
BS02 dna F T30 R36 R45 T15 R21 R30
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:6jma, PDBe:6jma, PDBj:6jma
PDBsum6jma
PubMed30923167
UniProtP62799|H4_XENLA Histone H4

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