Structure of PDB 6j4q Chain F

Receptor sequence
>6j4qF (length=246) Species: 9606 (Homo sapiens) [Search protein sequence]
FHVNKSGFPIDSHTWERMWMHVAKVHPKGGEMVGAIRNAAFLAKPSIPQV
PNYRLSMTIPDWLQAIQNYMKTLQYNHTGTQFFEIRKMRPLSGLMETAKE
MTRESLPIKCLEAVILGIYLTNGQPSIERFPISFKTYFSGNYFHHVVLGI
YCNGRYGSLGMSRRAELMDKPLTFRTLSDLIFDFEDSYKKYLHTVKKVKI
GLYVPHEPHSFQPIEWKQLVLNVSKMLRADIRKELEKYARDMRMKI
3D structure
PDB6j4q Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.
ChainF
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.17.17: tubulinyl-Tyr carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TQ8 F P138 G141 E144 P90 G93 E96
BS02 TQ8 F Y123 C158 F191 H193 S210 R211 H241 Y75 C110 F143 H145 S162 R163 H193
Gene Ontology
Biological Process
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005737 cytoplasm

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6j4q, PDBe:6j4q, PDBj:6j4q
PDBsum6j4q
PubMed31235911
UniProtQ86V25|VASH2_HUMAN Tubulinyl-Tyr carboxypeptidase 2 (Gene Name=VASH2)

[Back to BioLiP]