Structure of PDB 6hxj Chain F

Receptor sequence
>6hxjF (length=588) Species: 1092 (Chlorobium limicola) [Search protein sequence]
SILANKDTRAVIIGGVAGVNAAKRMAQFDFLVNRPLTVQAFVYPPEAGQQ
KEIFRGGELKNVTVYDSLAPALEEHPDINTALIYLGASRAAQAAKEALES
PNIQLVSMITEGVPEKDAKRLKKLAQKLGKMLNGPSSIGIMSAGECRLGV
IGGEFKNLKLCNLYRQGSFGVLTKSGGLSNEAMWLCAQNGDGITSAVAIG
GDAYPGTDFVTYLEMFEKDPATKAVVMIGEVGGNLEEEAAEWLAAEPRRI
KLIAAIGGTCQEVLGSARSKMNALRDAGAYVPDTFGGLSKEIKKVYEELI
AAGEISTEIDEAVLPELPPRVQEVMKQGEVIVEPLIRTTISDDRGEEPRY
AGYAASELCSKGYGIEDVIGLLWNKKLPTREESEIIKRIVMISADHGPAV
SGAFGSILAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKMAVEDYP
NDIPGFLSWMKKNVGPVPGIGHRVKSVKNPDQRVKYLVSYIKNETSLHTP
CLDYALEVEKVTTAKKGNLILNVDGTIGCILMDLDFPVHSLNGFFVLART
IGMIGHWIDQNNQNSRLIRLYDYLINYAVKPEQEVPEK
3D structure
PDB6hxj Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
ChainF
Resolution2.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.3.16: citrate synthase (unknown stereospecificity).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA F K480 P485 V486 I489 K534 K535 L538 K461 P466 V467 I470 K515 K516 L519
BS02 COA F Y44 P45 P46 Y85 L86 G87 R90 I110 E112 Y43 P44 P45 Y84 L85 G86 R89 I109 E111
BS03 FLC F H415 V419 F450 G451 H491 R502 R568 H396 V400 F431 G432 H472 R483 R549
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003878 ATP citrate synthase activity
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
Biological Process
GO:0006085 acetyl-CoA biosynthetic process
GO:0006099 tricarboxylic acid cycle
GO:0006629 lipid metabolic process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:6hxj, PDBe:6hxj, PDBj:6hxj
PDBsum6hxj
PubMed30944476
UniProtQ9AJC4

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