Structure of PDB 6ghv Chain F

Receptor sequence
>6ghvF (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
CHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNF
LQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVG
EEDCAEFSGNGWNDDKCNLAKFWICKKSAASC
3D structure
PDB6ghv Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis.
ChainF
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EZ8 F R309 S310 N311 R312 F374 R57 S58 N59 R60 F122 MOAD: Kd=52uM
BS02 EZ8 F F313 E347 N349 V351 G352 E354 E358 N365 D367 K368 F61 E95 N97 V99 G100 E102 E106 N113 D115 K116 MOAD: Kd=52uM
BS03 CA F E347 N349 E354 N365 D366 E95 N97 E102 N113 D114
BS04 CA F D320 E324 N350 E354 D355 D68 E72 N98 E102 D103
External links
PDB RCSB:6ghv, PDBe:6ghv, PDBj:6ghv
PDBsum6ghv
PubMed31469191
UniProtQ9NNX6|CD209_HUMAN CD209 antigen (Gene Name=CD209)

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