Structure of PDB 6f1t Chain F

Receptor sequence

>6f1tF (length=370) Species: 9823 (Sus scrofa) [Search protein sequence]

IANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDI
FIGPKAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEH
PVLLTEAPLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGV
VLDSGDGVTHAVPIYEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEGYDFH
SSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRF
RAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVLSGGSTL
FKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKM
WVSKKEYEEDGARSIHRKTF

3D structure

PDB

6f1t Cryo-EM shows how dynactin recruits two dyneins for faster movement.

Chain

Resolution

3.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	F	I30 G311 D312 L315 D325 K327 I328 R329 I330 S331 A332 Q334 E335 Y338	I24 G305 D306 L309 D319 K321 I322 R323 I324 S325 A326 Q328 E329 Y332
BS02	ADP	F	G17 K22 G161 D162 K215 K218 E219 G302 G303 L306	G11 K16 G155 D156 K209 K212 E213 G296 G297 L300

External links

PDB	RCSB:6f1t, PDBe:6f1t, PDBj:6f1t
PDBsum	6f1t
PubMed	29420470
UniProt	F2Z5G5\|ACTZ_PIG Alpha-centractin (Gene Name=ACTR1A)

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