Structure of PDB 6ezn Chain F

Receptor sequence
>6eznF (length=650) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SCVLSVFQTILKLVIFVAIFGAAISSRLFAVIKFESIIHEFDPWFNYRAT
KYLVNNSFYKFLNWFDDRTWYPLGRVTGGTLYPGLMTTSAFIWHALRNWL
GLPIDIRNVCVLFAPLFSGVTAWATYEFTKEIKDASAGLLAAGFIAIVPG
YISRSVAGSYDNEAIAITLLMVTFMFWIKAQKTGSIMHATCAALFYFYMV
SAWGGYVFITNLIPLHVFLLILMGRYSSKLYSAYTTWYAIGTVASMQIPF
VGFLPIRSNDHMAALGVFGLIQIVAFGDFVKGQISTAKFKVIMQPVSWPA
FFFDTHFLIWLFPAGVFLLFLDLKDEHVFVIAYSVLCSYFAGVMVRLMLT
LTPVICVSAAVALSKIFDIYLDFKIKPAALLAKLIVSGSFIFYLYLFVFH
STWVTRTAYSSPSVVLPSQTKLALIDDFREAYYWLRMNSDEDSKVAAWWD
YGYQIGGMADRTTLVDNNTWNNTHIAIVGKAMASPEEKSYEILKEHDVDY
VLVIFGGLIGFGGDDINKFLWMIRISEGIWPEEIKERDFYTAEGEYRVDA
RASETMRNSLLYKMSYKDFPQLFNGGQATDRVRQQMITPLDVPPLDYFDE
VFTSENWMVRIYQLKKDDAQGRTLRDVGELTRSSTKTRRSIKRPELGLRV
3D structure
PDB6ezn Molecular basis for glycan recognition and reaction priming of eukaryotic oligosaccharyltransferase.
ChainF
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.99.18: dolichyl-diphosphooligosaccharide--protein glycotransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CPL F S41 L105 R112 N113 L117 S36 L100 R107 N108 L112
BS02 CPL F L199 F202 Y203 L194 F197 Y198
Gene Ontology
Molecular Function
GO:0004576 oligosaccharyl transferase activity
GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0006486 protein glycosylation
GO:0006487 protein N-linked glycosylation
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0008250 oligosaccharyltransferase complex
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6ezn, PDBe:6ezn, PDBj:6ezn
PDBsum6ezn
PubMed36435935
UniProtP39007|STT3_YEAST Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3 (Gene Name=STT3)

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