Structure of PDB 6ey2 Chain F

Receptor sequence
>6ey2F (length=101) Species: 9606 (Homo sapiens) [Search protein sequence]
TNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHC
GGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLV
R
3D structure
PDB6ey2 Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs.
ChainF
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN F C300 C303 H320 C327 C47 C50 H67 C74
BS02 C3T F G306 T308 D309 W310 E314 Q319 W323 G53 T55 D56 W57 E61 Q66 W70
External links
PDB RCSB:6ey2, PDBe:6ey2, PDBj:6ey2
PDBsum6ey2
PubMed30055105
UniProtP98170|XIAP_HUMAN E3 ubiquitin-protein ligase XIAP (Gene Name=XIAP)

[Back to BioLiP]