Structure of PDB 6evj Chain F

Receptor sequence
>6evjF (length=746) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence]
SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMK
WMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTW
WNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDIN
PGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKI
SPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGG
EAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEIL
RSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGN
LQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLM
ITLMVFSQEEKMLKAVRGDLNFVNRANQRLNPMYQLLRHFQKDSSTLLKN
WGTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQGGVDEYSFNERIRVNI
DKYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTN
TYHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRT
LFQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLL
IRGNSQVFNYNQMENVIIVLGKSVGSPERSILTESSSIESAVLRGFLILG
KANSKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRKRDSSIL
3D structure
PDB6evj Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
ChainF
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna F I260 D304 F323 F357 E361 K376 F404 N429 Y432 S519 A521 I262 D306 F325 F359 E363 K378 F406 N431 Y434 S521 A523
BS02 rna F R38 E40 R46 W49 M53 R40 E42 R48 W51 M55
Gene Ontology
Biological Process
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6evj, PDBe:6evj, PDBj:6evj
PDBsum6evj
PubMed29202182
UniProtH6QM90

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