Structure of PDB 6el3 Chain F

Receptor sequence
>6el3F (length=364) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
FESVALIIGVTGIVGNSLAEILPLSDTPGGPWKVYGVARRPRPTWNADHP
IDYIQCDVSDAEDTRSKLSPLTDVTHVFYVTWTNRESESENCEANGSMLR
NVLQAIIPYAPNLRHVCLQTGTKHYLGPFTNVDGPRHDPPFTEDMPRLQI
QNFYYTQEDILFEEIKKIETVTWSIHRPNMIFGFSPYSLMNIVGTLCVYA
AICKHEGSPLLFPGSKKAWEGFMTASDADLIAEQQIWAAVDPYAKNEAFN
CNNADIFKWKHLWKILAEQFGIEEYGFEEGKNLGLVEMMKGKERVWEEMV
KENQLQEKKLEEVGVWWFADVILGVEGMIDSMNKSKEYGFLGFRNSNNSF
ISWIDKYKAFKIVP
3D structure
PDB6el3 PRISEs (progesterone 5 beta-reductase and/or iridoid synthase-like 1,4-enone reductases): Catalytic and substrate promiscuity allows for realization of multiple pathways in plant metabolism.
ChainF
Resolution1.899 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.3: Delta(4)-3-oxosteroid 5beta-reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP F G33 T35 G36 I37 A62 R63 R64 C80 D81 V82 T105 W106 Q143 T144 Y178 N203 I205 S212 L213 M214 G9 T11 G12 I13 A38 R39 R40 C56 D57 V58 T81 W82 Q119 T120 Y154 N179 I181 S188 L189 M190
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0035671 enone reductase activity
GO:0046983 protein dimerization activity
GO:0047787 Delta4-3-oxosteroid 5beta-reductase activity
Biological Process
GO:0008202 steroid metabolic process
GO:0009611 response to wounding
GO:0010051 xylem and phloem pattern formation
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6el3, PDBe:6el3, PDBj:6el3
PDBsum6el3
PubMed30172078
UniProtQ9STX2|VEP1_ARATH 3-oxo-Delta(4,5)-steroid 5-beta-reductase (Gene Name=VEP1)

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