Structure of PDB 6bfy Chain F

Receptor sequence
>6bfyF (length=438) Species: 562 (Escherichia coli) [Search protein sequence]
QMGRGSMSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIM
IDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKY
SMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLA
KVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLA
MDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLD
ESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFN
QIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKT
GSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
3D structure
PDB6bfy Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
ChainF
Resolution1.81 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S41 H158 E167 E208 D245 E289 D316 K341 H369 K392
Catalytic site (residue number reindexed from 1) S48 H165 E174 E215 D252 E296 D323 K348 H376 K399
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2PG F G39 A40 S41 H158 Q166 E167 E208 D245 D316 K341 H369 R370 S371 K392 G46 A47 S48 H165 Q173 E174 E215 D252 D323 K348 H376 R377 S378 K399
BS02 MG F D245 A247 D290 D316 D252 A254 D297 D323
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0005515 protein binding
GO:0016829 lyase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
GO:0006396 RNA processing
GO:0006401 RNA catabolic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0009986 cell surface
GO:0016020 membrane
GO:1990061 bacterial degradosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6bfy, PDBe:6bfy, PDBj:6bfy
PDBsum6bfy
PubMed30714720
UniProtP0A6P9|ENO_ECOLI Enolase (Gene Name=eno)

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