Structure of PDB 6b8o Chain F

Receptor sequence
>6b8oF (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
TTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEGPCQRVVSTHNLWL
LSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADTL
RKVLVEVLA
3D structure
PDB6b8o Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2.
ChainF
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PSF F S40 W44 T88 L89 S20 W24 T67 L68
External links
PDB RCSB:6b8o, PDBe:6b8o, PDBj:6b8o
PDBsum6b8o
PubMed29794134
UniProtQ9NZC2|TREM2_HUMAN Triggering receptor expressed on myeloid cells 2 (Gene Name=TREM2)

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