Structure of PDB 6b4i Chain F

Receptor sequence
>6b4iF (length=426) Species: 9606 (Homo sapiens) [Search protein sequence]
EDRAAQSLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQL
LQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML
SQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKL
ERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGH
QDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEET
LDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAEL
SKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVS
VVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILN
RIQEHFNKKIERLDTDDLDEIEKIAN
3D structure
PDB6b4i Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
ChainF
Resolution3.619 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP F R67 N69 L70 F112 S140 G141 G143 K144 T145 R14 N16 L17 F59 S87 G88 G90 K91 T92
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6b4i, PDBe:6b4i, PDBj:6b4i
PDBsum6b4i
PubMed29899397
UniProtQ9UMR2|DD19B_HUMAN ATP-dependent RNA helicase DDX19B (Gene Name=DDX19B)

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