Structure of PDB 6avg Chain F

Receptor sequence
>6avgF (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
REAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB6avg Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
ChainF
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F Y7 R62 I66 Y67 T73 S77 N80 L81 Y84 Y99 T143 K146 W147 E152 Q155 R156 Y159 W167 Y171 Y7 R62 I66 Y67 T73 S77 N80 L81 Y84 Y99 T143 K146 W147 E152 Q155 R156 Y159 W167 Y171
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:6avg, PDBe:6avg, PDBj:6avg
PDBsum6avg
PubMed29531227
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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